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HArmonyCa Hong Kong


LM SKINCENTRE Hong Kong introduces HArmonyCa dermal filler which is designed to restore facial volume and correct deficiencies by promoting the generation of natural endogenous collagen. HArmonyCa is based on a composite matrix of cross-linked Hyaluronic Acid embedding Calcium Hydroxyapatite microspheres.

What is the composition?

  • Calcium Hydroxyapatite (55.7%)
  • Sodium Hyaluronate gel (20 mg/ml), cross-linked (BDDE <2 ppm)
  • Lidocaine for extra comfort

What are the advantages of HArmonyCa?

  • Provides a strong volumising, lifting effect
  • Susceptible to Hyaluronidase
  • Reduced side effects, such as burning sensation, edema and pain
  • Promotes generation of natural collagen
  • Non-animal origin Hyaluronic Acid
  • Biocompatible and biodegradable

Special features of HArmonyCa:

One syringe

The concentration of each active ingredient is similar to that of Calcium Hydroxyapatite and Hyaluronic Acid dermal fillers combined in one syringe.


Collagen stimulation increases due to the combination of both active ingredients, providing a long lasting effect.


The presence of Hyaluronic Acid elevates skin hydration and moisture.


Calcium Hydroxyapatite is added during the cross-linking process, generating a stable, inseparable gel.


The Composite Matrix gel can prevent microspheres aggregation and dispersion, keeping the microspheres within their desired location


Calcium Hydroxyapatite stimulates collagen production, while Hyaluronic Acid forms a supporting extracellular matrix, which modulates fibroblasts proliferation.

What is the mechanism of action?

IMMEDIATE – A volumising effect and a full glowing look is immediately apparent due to the presence of Hyaluronic Acid.

LONG LASTING – The Calcium Hydroxyapatite microspheres form a scaffold supporting fibroblasts ingrowth. The Hyaluronic Acid binds to fibrin, which generates the supporting extracellular matrix. A “hyaline cartilage like” formation is generated by differentiating fibroblasts cells into chondroblasts, which deposit endogenous collagen- the natural lifting agent of the skin. Degradation of the gel is synchronous with neo-collagen production resulting in a natural, youthful, long-lasting appearance.

What is the structure under microscope?

HArmonyCa composite matrix is comprised of Calcium Hydroxyapatite microspheres that are strongly embedded within high quality cross linked Hyaluronic Acid.

  • The Calcium Hydroxyapatite microspheres are round, non-porous and smooth, enabling easy extrusion.
  • The microsphere diameter (25-45 microns) minimizes risk of particle migration and phagocytosis which, in addition to the microspheres’ integration within a net of cross-linked Hyaluronic Acid, ensures a smooth appearance.
  • Microspheres embedded within cross-linked Hyaluronic Acid helps preserve the balance between microsphere consolidation and dissemination.

Questions and Answers

What is HArmonyCa™?

HArmonyCa™ is a dual-effect Hybrid Injectable, containing calcium hydroxyapatite (CaHA) and hyaluronic acid (HA), designed to improve skin architecture by providing both an immediate lift effect from HA and sustained lifting from new collagen production with CaHA.

How do HA and CaHA in HArmonyCa™ work?

HA particles provide an immediate lift effect by plumping up the skin, while CaHA particles support collagen production, leading to a gradual and long-lasting lift as a firm and dense collagen network replaces the gel over time.

What does the HArmonyCa™ procedure involve?

The procedure involves assessing your suitability for HArmonyCa™, followed by injections in targeted facial areas. HArmonyCa™ contains lidocaine to reduce pain during treatment.

How long does HArmonyCa treatment take?

A treatment takes approximately 30 minutes allowing you to go straight back to your normal daily life.

What facial areas can be treated with HArmonyCa™?

HArmonyCa™ can be used in deep dermal and sub-dermal layers of certain facial areas, but not around the eyes, lips, or mouth. The specific areas for treatment will be determined during your consultation.

How is HArmonyCa™ different from other biostimulators or dermal fillers?

Unlike biostimulators or HA dermal fillers, HArmonyCa™ combines the benefits of both HA and CaHA, offering an immediate lift and lasting collagen production in one injection.

What are the pre- and post-treatment care instructions for HArmonyCa™?

Pre-treatment instructions will be provided during your consultation. Post-treatment, avoid high-intensity activities and extreme weather conditions for 24 hours, use ice packs to reduce swelling, and massage treated areas if needed.

What should I do following HArmonyCa treatment?

It is recommended to avoid hot bathing and vigorous exercise for 24 hours and over-exposure to the sun and UV light for 1 week after treatment.

Can HArmonyCa™ be combined with other treatments?

The compatibility of HArmonyCa™ with other treatments will be discussed during your personalized treatment plan consultation.

Is the HArmonyCa™ procedure painful?

HArmonyCa™ contains lidocaine to minimize pain, but pain tolerance varies between individuals.

What results can I expect from HArmonyCa™?

HArmonyCa™ may offer an immediate lifting effect and stimulate collagen production. Most patients report improvements in facial appearance after treatment.

How many sessions are generally needed for HArmonyCa treatment?

With HArmonyCa, only one session is needed to obtain immediate results and long-lasting correction.

Is HArmonyCa™ suitable for me?

HArmonyCa™ is potentially suitable for individuals showing signs of aging and needing facial soft tissue augmentation. Suitability will be determined during your consultation.

How do I know if I would benefit from HArmonyCa™?

Your healthcare professional will assess your specific facial concerns and determine if HArmonyCa™ is suitable for you during the consultation.

What are the side effects of HArmonyCa™?

Common side effects include redness, swelling, pain, and itching, usually subsiding within 24-48 hours. Less common side effects will be discussed during your consultation.

How do HA and CaHA work in HArmonyCa™ compared to other fillers?

HA provides an immediate lift, while CaHA supports collagen production, offering benefits that single-agent treatments like HA injections or biostimulators may not provide.

Why should I consider treatment with HArmonyCa™?

HArmonyCa™ may improve skin architecture, offering both an immediate lift and sustained lifting effect through new collagen production.

Will I feel pain during the HArmonyCa™ injection?

The inclusion of lidocaine in HArmonyCa™ is intended to reduce pain, though individual pain tolerance can vary.

Are there any serious potential side effects of HArmonyCa™?

While most side effects are mild, other adverse events may require surgical intervention, such as in cases of severe allergy, inflammation, hypersensitivity, or infection.

What is the price of HArmonyCa treatment in Hong Kong?

It depends on the number of HArmonyCa syringes you require. For more information about the price, contact us for more details.