LM SKINCENTRE Hong Kong introduces Relfydess, which is a next-generation neuromodulator treatment designed to temporarily improve moderate to severe frown lines between the eyebrows and crow’s feet at the outer corners of the eyes. It is a ready-to-use liquid formulation developed by Galderma, with some patients seeing effects from Day 1 and sustained improvements reported through 6 months in clinical studies.
What is Relfydess?
Relfydess is the brand name for RelabotulinumtoxinA, a botulinum toxin type A neuromodulator. Galderma describes it as the first and only ready-to-use liquid neuromodulator created with PEARL™ Technology.
How does Relfydess work?
Relfydess works by inhibiting nerve signals that trigger muscle contraction. By temporarily reducing the activity of targeted facial muscles, it can soften the appearance of dynamic lines such as glabellar lines and lateral canthal lines.
What can Relfydess treat?
As of today, Relfydess is indicated for the temporary improvement in the appearance of:
– Glabellar lines at maximum frown
– Lateral canthal lines at maximum smile, commonly called crow’s feet
*Approved indications can vary by country and time.
Why choose Relfydess?
1. Fast onset
In the Phase III READY-1 study, 39% of treated participants reported visible effect by Day 1, with a median time to onset of 2 days for glabellar lines.
2. Sustained results
Galderma’s materials report that up to 75% of patients treated for glabellar lines maintained improvements through 6 months, with sustained results also reported for lateral canthal lines. The READY-1 trial likewise showed effectiveness through Month 6 for the majority of treated participants.
3. Ready-to-use liquid formulation
Unlike products that require reconstitution before use, Relfydess is supplied as a ready-to-use liquid.
4. PEARL™ Technology
Galderma states that Relfydess is designed with PEARL™ Technology to preserve molecule integrity and deliver a highly active formulation.
What to expect from a Relfydess consultation
A proper consultation should assess your facial movement, line severity, treatment goals, and medical history. Relfydess should only be administered by a qualified doctor, and patients should discuss other medical conditions, medications, pregnancy plans, or breastfeeding with their doctor before treatment.
Safety and side effects
Commonly reported adverse reactions include headache and injection-site reactions such as bruising, swelling, pain, discomfort, warmth, pruritus, or haematoma. People with an allergy to botulinum toxin A products, or an infection at the proposed injection site, should not receive treatment.
Why choose Reflydess for Relfydess treatment?
At Reflydess, every treatment plan should begin with careful facial assessment and a personalized approach. Relfydess may suit patients who want a modern neuromodulator option for frown lines and crow’s feet, especially those interested in a ready-to-use liquid formulation and clinical data showing rapid onset and sustained improvement.
Frequently Asked Questions
Is Relfydess the same as Botox?
No. Relfydess is a different botulinum toxin type A product, branded as relabotulinumtoxinA. Official product information states that botulinum toxin units are not interchangeable from one product to another.
How soon will I see results from Relfydess?
Clinical data showed that some patients noticed effects from Day 1, and the median onset in the READY-1 glabellar line study was 2 days. Individual response can vary.
How long does Relfydess last?
Official Galderma materials report sustained improvements through 6 months in many patients, with up to 75% of glabellar-line patients maintaining improvements through that time point in cited analyses.
What areas can Relfydess treat?
It is approved and indicated for glabellar lines and lateral canthal lines (crow’s feet) but other areas can be used for off-label use after proper discussion with your doctor.
What makes Relfydess different?
Key differentiators highlighted by Galderma include its ready-to-use liquid formulation, PEARL™ Technology, and simple volumetric dosing without reconstitution.
Is Relfydess safe?
Official clinical and prescribing sources describe Relfydess as having a favorable or demonstrated safety profile when used appropriately, but side effects can occur. Common side effects include headache and injection-site reactions such as bruising or swelling.
Who should avoid Relfydess?
Treatment should not be given to people who are allergic to botulinum toxin A products or who have an infection at the proposed injection site. Patients should also discuss medicines, medical conditions, pregnancy, and breastfeeding with their doctor before treatment.
Can Relfydess give natural-looking results?
In the Phase III study, most participants reported high satisfaction with how natural their face looked after treatment around peak effect, and satisfaction remained high through the study period.